Parasites of Medical Importance (Landes Bioscience Medical by A.J. Nappi

By A.J. Nappi

Parasites Parasitology is the study
of eukaryotic parasites.

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1955. Bayer, Leverkusen, Germany. Unfortunately, very little is known of the factors influencing gametogenesis. These immature gametocytes typically are present in circulating red blood cells after a few to several erythrocytic schizogonic cycles. They remain as gametocytes within the erythrocytes and do not mature further Apicomplexa: Sporozoa and Piroplasmea 31 4 Figure 4B. Intracellular developmental stages of Plasmodium. From Microscopic Diagnosis of Tropical Medicine. 1955. Bayer, Leverkusen, Germany.

Within the miracidium, a mass of germinal tissue provides the cell lineage for succeeding stages in the life cycle. Upon entering the molluscan intermediate host, the miracidium sheds its ciliated covering, elongates and transforms into either a saclike first-generation (mother) sporocyst, or in some species a slightly more advanced stage called a redia. Germ cells within the body of the mother sporocyst or redia develop into either second generation (daughter) sporocysts or rediae. Germinal cells in the daughter sporocysts or rediae eventually give rise to cercariae, the final 38 Parasites of Medical Importance 5 Figure 2.

Their eggs enter the lymphatic and circulatory passages and are transported to various organs, including the heart, brain and spinal cord, where granulomatous responses are provoked. Heart damage (heterophyid myocarditis) may result from the accumulation of numerous eggs in the organ. Echinostomate flukes are characterized by a collar of spines on a disk surrounding the oral sucker. The parasites have been reported from the Philippines and China, where dogs are commonly infected. Operculated eggs are voided in the feces of the definitive host.

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