Gastroenteritis Viruses by Novartis Foundation

By Novartis Foundation

This significant e-book covers the constitution and molecular biology of small around based viruses (SSRVs) comparable to caliciviruses and astroviruses, and the elemental pathology of an infection. It offers readers with the information had to make development within the prevention and remedy of those infections. Readers also will locate an summary of gastroentitis vaccines, their constitution and molecular biology, in addition to the fundamental pathology of an infection, epidemiology and surveillance.* presents an interdisciplinary method, delivering contributions from simple and scientific study* Discusses the prevention and remedy of regimes* contains an outline of gastroentitis vaccines

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We were unable to find any clear correlation. Of course, this was for group A rotavirus and we were not assessing group C, which is far less common than group A. Desselberger: Bernard Fields looked at this for reoviruses, and stated in his last publication that there was no association between biliary atresia and reoviral infection (Tyler & Fields 1996). GLass: Rotavirus may cause other severe diseases also. For instance, the Japanese observed seizures in patients with rotavirus diarrhoea (Ushijima et a1 1994).

I have some results from collaborative work in Santiago, Chile with Miguel O’Ryan (O’Ryan et a1 2000). When they first looked at a large set of hospital specimens, they found just one calicivims case using RT-PCR and primers NV35, NV36 and other pairs, out of hundreds of samples. This was a disappointing result. We sequenced the 35/36 product of that single case and aligned it with all the known 35/36 regions that we could find. It turned out that this strain was an SLV in a new clade. We came up with a new primer pair (p289/ 290).

Lancet 349:1436-1442 Nakagom T, Nakagomi 0 1989 RNA-RNA hybridization identifies a human rotavirus that is genetically related to feline rotavirus. J Virol63:1431-1434 Pang X-L, Honma S, Nakata S, Vesikari T 2000 Human caliciviruses in acute gastroenteritis of young children in the community. J Infect Dis (suppl2) 181:S288-S294 Pereira HG 1991 Double-stranded RNA viruses. Semin Virol2:39-53 Rosen BI, Fang 2-Y, Glass RI, Monroe SS 2000 Clonmg of human picorbmavirus gene segments and development of an RT-PCR detection assay.

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