Biochemical Disorders of the Skeleton by Roger Smith, Paul Wordsworth
By Roger Smith, Paul Wordsworth
This booklet offers with these issues of the skeleton linked to identified biochemical abnormalities of its parts. It comprehensively covers universal polygenic and infrequent monogenic issues and emphasizes the hot advances which were made in bone mobilephone biology and in human skeletal ailment really due to molecular medication. This has been accomplished inside an simply readable and well-illustrated e-book. it truly is written for the postgraduate and clinician who reveals issues of the skeleton mysterious and for whom an comprehensible clarification isn't really continuously on hand. will probably be of specific curiosity to people who take care of sufferers with a wide selection of metabolic bone ailments, together with rheumatologists, endocrinologists and orthopedic surgeons, and comprises new details of curiosity to pediatricians and geneticists. This department of medication is at the moment now not good taught or even the skilled clinician won't have encountered a few of these issues.
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Additional info for Biochemical Disorders of the Skeleton
1973). The cellular basis of metabolic bone disease. Med. 289,25-32 Rasmussen, H. and Bordier, Ph. (1974). The Physiological and Cellular Basis of Metabolic Bone Disease. Baltimore: Williams and Wilkins Co. Reeve, J. (1977). Disorders of plasma calcium. Hosp. Update. 3, 19-30 Russell, R. G. G. (1975). Diphosphonates and polyphosphates in medicine. Br. J. Hosp. Med. 14,297-314 Russell, R. G. G. and Fleisch, H. (1976). Pyrophosphate and diphosphonates. In The Biochemistry and Physiology of Bone.
5 μ%) for adults. 13*. 14). The further metabolism of vitamin D (either D2 or D3) has been well described by Kodicek (1974) and subsequently by many others (see Haussler and McCain, 1977). 15) are first a 25-hydroxylation by microsomal enzyme systems in the liver and then an important 1 a-hydroxylation (at the *The nomenclature of vitamin D metabolites differs according to the author. The main alternatives are: for 25-hydroxycholecalciferol - 25 HCC or 25(OH)CC or 25(OH)D; and for 1,25-dihydroxycholecalciferol - 1,25 DHCC, 1,25 (OH)2D or 1,25 (OH)2CC.
Biochemistry and clinical applications. Ann. intern. Med. 66,1243-1267 Queener, S. F. and Bell, N. H. (1975). Calcitonin: a general survey. Metabolism 24, 555-567 Rasmussen, H. and Bordier, Ph. (1973). The cellular basis of metabolic bone disease. Med. 289,25-32 Rasmussen, H. and Bordier, Ph. (1974). The Physiological and Cellular Basis of Metabolic Bone Disease. Baltimore: Williams and Wilkins Co. Reeve, J. (1977). Disorders of plasma calcium. Hosp. Update. 3, 19-30 Russell, R. G. G. (1975). Diphosphonates and polyphosphates in medicine.