A History of Gastric Secretion and Digestion: Experimental by Horace W. Davenport

By Horace W. Davenport

This e-book examines the heritage of experimental research in gastric secretion and digestion. the writer identifies the clinical questions that experience occupied researchers and discusses the experiments that experience ended in their options. by way of separating features of experimental examine and tracing their evolution through the years, the e-book presents gastric physiologists and gastroenterologists with a superior realizing of the highbrow historical past in their box.

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F"" Strommeier Figure 1-9. Torsten Teorell's model illustrating his method of accounting for variations in the concentration of gastric juice by back-diffusion of acid. Luft = air; Strommeter = flow meter; Glasrohr = glass tube; Pergament = semipermeable membrane. (From Teorell T. Untersuchungen über die Magensaftsekretion. J 4 s 6 7 8 9 10 mtl,omil Sflcrfllion ratfl Figure 1-10. Primary acidity in a dog's stomach determined by catching newly secreted hydrogen ions with glycine buffer and then by dividing the titer of the buffer by the volume increment.

I 1·0 0·8 0·6 ' I ' I I ' ,I • I 0·4 0·2 I 0 0 • • • ••• • •• 8 16 24 3? 40 48 56 Figure 1-17. Ordinates, carbonic anhydrase concentration in arbitrary units in slices of gastric mucosa of the cat in excess ofthat predicted from the number of oxyntic cells in adjacent slices. The broken line is the relation between enzyme concentration and oxyntic cell count from Figure 1-16. Abscissae, 1,000 surface epithelial cells in adjacent slices of oxyntic mucosa of the cat. (From Davenport HW. Gastric carbonic anhydrase.

E• 3 4 _: 2 3 4 5 6 7 ·?! 11 J .. 4 5 _,F'"· . I II 7 c Figure 1-15. A: Ordinates, ratio of the concentration of iodide in gastric juicetothat in plasma. Abscissae, plasma iodide concentration in millimoles per Iiter. B: Ordinates, gastric juice iodide cci_ncentration in millimoles per Iiter. Abscissae, plasma iodide concentration in millimöles per Iiter. C: Ordinates, ratio of iodide concentration in plasma tothat in gastric juice. Abscissae, plasma iodide concentration in millimoles per Iiter.

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